GUIDELINES FOR SYSTEMIC TREATMENT OF PATIENTS WITH PSORIASIS AT THE UNIVERSITY CLINIC FOR DERMATOLOGY – SKOPJE

Authors

  • Tomica Sotirovski University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia
  • Viktor Simeonovski University Clinic for Dermatology, Skopje, North Macedonia, Medical Faculty, University "Ss. Cyril and Methodius" Skopje, Skopje, North Macedonia
  • Katerina Damveska University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia
  • Nebojsha Peshikj University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia
  • Elena Mircheska Arsovska University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia
  • Dejan Filipovikj University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia
  • Bojana Batkoska Shekutkoska University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia
  • Anita Najdova University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia
  • Tomche Popovski University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia
  • Kamelija Doneva Simonov University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia
  • Ema Stoicovska University Clinic for Dermatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia

Keywords:

psoriasis, guidelines

Abstract

Psoriasis is a chronic autoimmune disease that causes inflammation in your skin and encompasses several disease subtypes (plaque, inverse, guttate, pustular, erythrodermic, nail and sebopsoriasis), requiring a standardized approach to diagnosis and treatment. According to current recommendations, the treatment involves the use immunosuppressants and biologic therapy which has already been approved as a first-line treatment for moderate to severe psoriasis in Europe and USA. These guidelines are made for the needs of the University Clinic for Dermatology – Skopje and are based on the European guidelines on the systemic treatment of psoriasis (EuroGuiDerm Guidelines on the systemic treatment of Psoriasis vulgaris, 2020). They include a system for grading disease severity, and recommendations for treatment and monitoring.  Systemic treatment modalities included in these guidelines are: acitretin, ciclosporin, methotrexate, adalimumab, apremilast, brodalumab, certolizumab, pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, secukinumab, tildrakizumab and ustekinumab.

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Published

2025-06-12

Issue

Section

Guidelines