SAPS 2 SCORE VALID PARAMETER FOR OUTCOME IN SEVERE INFLUENZA

Authors

  • Marija Cvetanovska 1University Clinic for Infectious Diseases and Febrile Conditions, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia
  • Ilir Demiri University Clinic for Infectious Diseases and Febrile Conditions, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia
  • Krsto Grozdanovski 1University Clinic for Infectious Diseases and Febrile Conditions, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia
  • Katerina Spasovska 1University Clinic for Infectious Diseases and Febrile Conditions, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia
  • Vlatko Cvetanovski General Hospital Remedika, Skopje, R. North Macedonia

Keywords:

Severe influenza, SAPS II score

Abstract

The aim of study was to identify the significance of SAPS 2 score admission values on outcome in severe influenza.

Materials and methods: The investigation was prospective, group comparison, con­duc­ted at the University Clinic for Infectious Diseases, Skopje in a three-year period. The study included adult patients with severe influenza divided in two groups, survived and deceased. Demographic, clinical and biochemical data were noted on admission. The variables of the univariate analysis that showed a significant difference in terms of the outcome were used for creating multivariate logistic and regression analysis of the outcome as dependent factors. The independent predictors for lethal outcome in severe cases of influenza were identified by using logistic regression.

 Results: The study included 87 patients with clinical and laboratory confirmed severe influenza divided in two groups: survived (n=75) and deceased (n=12). The overall mortality was 13.79%. Multivariate analysis conducted on admission identified SAPS II score (p=0.048) as independent predictor of the outcome in severe influenza. The increase of the SAPS II score in one point increased the chance of death in patients with influenza by 1.2% (OR=1.12 95% CI 1.01-2.976).

Conclusion: In our study the SAPS II score has been identified as an independent va­riab­le, which has predicted the outcome in patients with severe influenza on hospital admission.  The early identification of the outcome predictors in patients with severe influenza will ensure implementation of adequate medical procedures, and also, it will contribute to decreasing the mortality of this disease.

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Published

2021-12-27 — Updated on 2021-12-30

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Issue

Vol. 1 No. 2 (2021): Acad Med J

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Original Articles