COMPARATIVE ANALYSIS OF PREOPERATIVE AND POSTOPERATIVE DIAGNOSIS IN SKIN MELANOMA

Authors

  • Lazo Noveski University Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia
  • Boro Dzonov University Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia
  • Elizabeta Mirchevska University Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia
  • Margarita Peneva University Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia
  • Vladislav Gruev University Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia
  • Jasmina Dobrevska University Clinic for Plastic and Reconstructive Surgery, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R. North Macedonia

Keywords:

melanoma, dermoscopy, misdiagnosis, pathohistology

Abstract

Introduction: Taking into account the increase in incidence and high mortality in advanced stages, early diagnosis is a prerequisite for successful treatment of melanoma.

The aim of this study was to determine the concordance between dermatological (with dermoscopy), surgical and pathohistological diagnosis in patients with a suspicious finding of skin melanoma.

Material and methods: A comparison between the clinical and pathohistological diagno­sis of patients of both sexes, of all ages, with a referral diagnosis of skin melanoma was made.

Results: Out of a total of 535 analyzed cases, 469 (87.5%) had preoperative dermato­lo­gical findings. In 329 of these patients the referral diagnosis was in favor of melanoma. In 140 cases with a dermatological finding other than melanoma, a pathohistological finding of melanoma was obtained, 30% with a dermatological finding.

In addition to melanoma, in 289 cases out of 329 cases with dermatological findings a pathohistological finding for melanoma was obtained, and in 40 cases a pathohistological finding other than melanoma was obtained.

Of 66 cases without dermatological findings, 27 patients with a surgical diagnosis other than melanoma were operated on, with a pathohistological finding for melanoma - 41%. With a diagnosis of melanoma without prior dermatological examination, 39 cases were operated on, of which in 12 cases the pathohistological finding was in support of melanoma.

Of 58 patients who underwent dermoscopy, 78% had a matching dermoscopic and pa­thohistological diagnosis.

Conclusion: The results of this study showed a high percentage of erroneous pre­ope­ra­tive diagnoses.

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Published

2021-12-27 — Updated on 2021-12-30

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Issue

Vol. 1 No. 2 (2021): Acad Med J

Section

Original Articles